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what is doxycycline hyclate br Material and methods br Resul
2023-10-25

Material and methods Results Discussion RSV is a major cause of lower respiratory tract infections in infancy and early childhood. Several observations suggest that immunological mechanisms may be the key to understand the severity of RSV bronchiolitis in infancy. Several laboratories have
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We also measured macrophage infiltration
2023-10-25

We also measured macrophage infiltration and CLS presence in peri-gonadal AT from db/db mice and controls. CLS are morphological features within AT that are accurate indicators of adipocyte death and macrophage infiltration [56]. An earlier study showed that CLS macrophages account for >90% of the t
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Gratifyingly compound also demonstrated improved
2023-10-25

Gratifyingly, compound also demonstrated improved physicochemical properties with significant improvement in aqueous solubility. Compound was sufficiently potent to determine its pharmacokinetic (PK) and pharmacodynamics (PD); data is summarized in . shows ADME characteristics for compound and
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Polycyclic aromatic hydrocarbons PAHs are
2023-10-25

Polycyclic aromatic hydrocarbons (PAHs) are abundant environmental contaminants that are produced by the incomplete combustion of organic matter, combustion engines, residential heating, 2665 synthesis burning, and industrial activities (Gelboin, 1980; Phillips, 1999, Phillips, 2002). Some PAHs have
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Introduction hydroxytryptamine HT is found throughout the bo
2023-10-25

Introduction 5-hydroxytryptamine (5-HT) is found throughout the body and influences smooth muscle activity in various tissues including the intestine, vasculature and urinary s7694 (Kim and Camilleri, 2000, Klarskov and Horby-Petersen, 1986, Mohammad-Zadeh et al., 2008). The current classification
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Introduction The MMR system keeps the fidelity of replicatio
2023-10-24

Introduction The MMR system keeps the fidelity of replication by repairing replication errors such as base-base mispairs and insertions/deletions. It plays a substantial role in restoring the fidelity of DNA and contributing to genome integrity [1]. The components of MMR are conserved in a broad ra
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br Materials and methods br Results and
2023-10-24

Materials and methods Results and discussion Conclusion The preparation of acrylic nanoparticles as aminosugar carriers could not be achieved by direct functionalization of poly(t-butyl acrylate) particles with saccharide groups. A four-step procedure starting from a protected derivative of
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Tetracyclines constitute one of the most
2023-10-24

Tetracyclines constitute one of the most important antibiotic groups used as veterinary and human medicine and as feed additives in the agricultural sector (Li et al., 2011a, Simon, 2005). Annual worldwide production of tetracyclines is estimated to be in the thousands of tons (Michalova et al., 200
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br Identification of the croaker mAR cDNA Testosterone T was
2023-10-24

Identification of the croaker mAR cDNA Testosterone (T) was observed to alter steroidogenesis through a nongenomic mechanism (not blocked by the transcription inhibitor, actinomycin D) in Atlantic croaker ovarian tissues (Braun and Thomas, 2003). This action of T was mimicked by T conjugated to B
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In another study Yerra and Kumar used streptozotocin
2023-10-24

In another study, Yerra and Kumar (2016) used streptozotocin to induce diabetic neuropathy in rats. Mechanical/thermal hyperalgesia, motor/sensory nerve conduction velocities (MNCV and SNCV) and sciatic nerve blood flow (NBF) were evaluated. In vitro studies of Neuro2a (N2A) cell culture were perfor
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Circular dichroism CD provides useful information about prot
2023-10-24

Circular dichroism (CD) provides useful information about protein structure, the extent and rate of structural changes and ligand binding. CD is a form of light cystamine spectroscopy that measures differences in the absorbance of right- and left-circularly polarized light (rather than the commonly
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Despite extensive studies on the
2023-10-24

Despite extensive studies on the expression of T. pallidum-induced pro-inflammatory cytokines, very little is known about T. pallidum-mediated intracellular signaling pathway activation, that leads to cytokine expression in macrophages. A network of signaling molecules, transcription factors, epigen
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br Materials and methods br Results and discussion First
2023-10-24

Materials and methods Results and discussion First, we examined whether hypothalamic Akt-mediated signaling pathways are regulated postprandially in chickens. Refeeding significantly (P STF 31 concentrations significantly increased in chicks after 1 h of refeeding (958 ± 245% of 24 h-fasting
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br Adiponectin in prostate cancer PC was
2023-10-24

Adiponectin in prostate cancer PC was documented as the leading type of malignancy in males in the US with respect to both the estimated number of cases (22,800) and deaths (27,540) (Siegel et al., 2016). Studies have reported an association between low APN levels and the progression of PC (Micha
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Since natural and recombinant glycoprotein
2023-10-24

Since natural and recombinant glycoprotein hormones exhibit some differences in their carbohydrate structures, we checked whether this could affect the permissive effect on FSK-induced cyclic AMP response in MLTC-1 cells. Fig. 6 shows that the same sensitizing effect to FSK is observed with pituitar
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