• CGP 3466B maleate A growing number of other

  2019-08-08

  

  A growing number of other post-translational modifications are implicated in regulation of the ubiquitin system, including substrate modification by hydroxylation, glycosylation, acetylation, methylation, modification by poly(ADP-ribose) (PAR), and attachment of ubiquitin-like modifiers. The HIF1-α

• Recent studies showed that the activity

  2019-08-07

  Recent studies showed that the activity of CK2 was significantly reduced in ischemic stroke model rats, and cerebral I/R injury significantly decreased the expression of CK2α (Lee et al., 2004; Kim et al., 2012; Zhou et al., 2016).

• Acknowledgement Introduction Recent developments

  2019-08-06

  Acknowledgement Introduction Recent developments in cancer immunotherapies have demonstrated durable responses, suggesting that effective immunotherapy would hold promise to improve patient outcome (Gunturu et al., 2013; Hodi et al., 2003; Lutz et al., 2011; Ribas et al., 2009).

• Some natural products such as curcumin resveratrol and sulfo

  2019-08-05

  Some natural products, such as curcumin, resveratrol, and sulforaphane, are known to activate Nrf2 in both in vivo and in vitro experimental models where Nrf2-mediated gene TAK-438 plays a crucial protective role [8].

• So far few studies have

  2019-08-02

  So far few studies have been conducted on the role of chemokines in patients with PTSD and avoidant personality disorders.

• The differences between ground and transition state

  2019-08-01

  The differences between ground and transition state properties are exemplified by a comparison of our human–yeast results with those of a structural study of possible differences in ubiquitin-Uba-1 binding in yeast (known structure) with human (simulated in [12]).

• TCS 359 Herein we explored by docking

  2019-07-31

  Herein, we explored by docking studies the effectiveness of replacing the dimethyl substitution at C (6) of dihydrotriazine with a folded azaspiro-containing substituent, along with the introduction of differently substituted phenyl- and benzyl-rings or alkyl chains, linked at the position 1 of the main core of the derivatives (see Fig. 1, Fig. 2, Fig. 3).

• Study design Results To explore potential differences in

  2019-07-30

  Study design Results To explore potential differences in the volume the different swabs absorb, the loss of weight of tubes filled with water after soaking the different swabs under defined conditions was determined.

• Results Discussion Experimental

  2019-07-27

  Results Discussion Experimental Procedures Author Contributions Acknowledgments Introduction Excitatory synaptic transmission within the brain is largely mediated by ionotropic glutamate receptors.

• As mentioned above EBI and its ligand show

  2019-07-26

  As mentioned above, EBI2 and its ligand show some similarities to the sphingosine 1-phosphate (S1P)/S1P-receptor system, which mediates T cell egress from lymph nodes.

• Apoptosis Inhibitor Case report The patient was referred to

  2019-07-25

  Case report The patient was referred to the oral and maxillofacial department at the authors’ institution for further evaluation and treatment.

• At the same time that the

  2019-07-24

  At the same time that the CPA education requirements have been increasing, the composition of the post-secondary student population has experienced a substantial increase in the number and relative proportion of students who delay college or university matriculation.

• The repair pathway of DNA

  2019-07-23

  The repair pathway of DNA-DSBs through HR and the role of BRCA1 in repair kinetics by HR is also an important factor to unravel the radiation sensitization of novel small molecule inhibitors.

• Roles for intracellular chloride channels

  2019-07-22

  Roles for intracellular chloride channels Specific chloride channel proteins in intracellular membranes Concluding remarks Introduction

• Unlike CRM exportins Cse and Xpot

  2019-07-19

  Unlike CRM1, exportins Cse1 and Xpot lack a C-extension and instead rely primarily on changes in HEAT-repeat conformation and direct Ran-cargo contacts to ensure low cargo-binding affinity in the cytosol and cooperative assembly of the exportin/Ran/cargo complex in the nucleus (Cook et al., 2005, Cook et al., 2009, Matsuura and Stewart, 2004).

14900 records 993/994 page Previous Next First page 上5页 991992993994